Genetic changes in Crohn’s point to future treatments
The discovery of genetic changes in Crohn’s disease (CD) could lead to new treatments, say UK scientists.
The researchers from the University of Edinburgh performed a genome-wide study in children with newly diagnosed untreated CD.
They found a highly significant enrichment of methylation changes around GWAS single nucleotide polymorphisms in the HLA region and MIR21. These contained genes responsible for immune and cellular functions