Guillain-Barré link to Gardasil queried

GARDASIL vaccination has been linked to a higher than average risk of developing Guillain-Barré syndrome (GBS) in a US study of adverse event reports.

Researchers relied mainly on data from the Vaccine Adverse Events Reporting System (VAERS) in determining that the average weekly reported rate of GBS within six weeks of receiving the quadrivalent HPV vaccine was 6.6 events per 10 million recipients.

This compared with an average weekly incidence rate of <2.6 per 10 million people in the community, they said.

But Centers for Disease Control officers said the reporting rate may have been inflated because of the authors’ “questionable” assumption that everyone vaccinated received the entire three-dose course.

The VAERS system may include inaccurate reports, while temporal association of an adverse event with vaccination did not prove causality, they wrote in a letter.

Gardasil manufacturer CSL said the