High BP in elderly linked to brain pathology

Higher blood pressure late in life is associated with more brain infarcts and with Alzheimer disease pathology, researchers report.

A US team investigated the role of both mean and change in late-life blood pressure in relation to brain pathology in nearly 1300 participants in their 80s in three ongoing, prospective, community-based cohort studies of aging.

The mean blood pressure at baseline was 136/72 mm Hg, and during eight years of follow-up, systolic blood pressure declined a mean 0.8 mmHg per year and diastolic blood pressure declined a mean 0.1