High-dose calcium supps may increase CV deaths in men
A study tracked 388,229 adults aged 50–71 who participated in the National Institutes of Health AARP (American Association for Retired Persons) Diet and Health Study for a mean of 12 years. During follow-up, 7904 and 3874 deaths occurred in men and women respectively.
Calcium supplements were used by 51% of men and 70% of women. Men who took more than 1000mg a day had a 20% increased risk of cardiovascular disease death (RR 1.20) and a 19% increased risk of heart disease death (RR 1.19), compared to non-users.
BMJ 2013; online 4 Feb