High potency of kids’ Fluvax a concern

THE trivalent influenza vaccine that caused a spate of febrile convulsions in children last year has been found to be a potent immunostimulant even in very diluted concentrations, researchers say.

In a study independent of the official investigation, Perth-based scientists used blood samples from children aged under two years who suffered convulsions after being administered CSL’s Fluvax or Fluvax Junior, to observe interaction in vitro.

“[The] 2010 Fluvax was a potent immunostimulator… even when diluted 250-fold,” the scientists told a conference last week.

“Preparations of Influvac (Abbott) and Vaxigrip (Sanofi) were only weakly stimulatory, even in the highest concentration used.”

Investigator Associate Professor Chris Blyth, from the School of Paediatrics and Child Health at the University of Western Australia, said it was difficult to know what would be considered “normal” in such an