High testosterone levels cut stroke risk

Low plasma testosterone (T) and dihydrotestosterone (DHT) are “independent and substantive predictors” of incident stroke in older men, say WA researchers.

Their population-based study of 3,700 men aged 70 to 89 shows those in the highest compared with the lowest quartile for T and DHT had roughly half the risk of a first stroke, with a mean follow up of nearly seven years.

The finding held even after adjusting for age, cardiovascular risk factors, anticoagulation therapy and head injury on admission for stroke.

The researchers led by Professor Bu Yeap, an endocrinologist at the University of Western Australia, also found higher rates of myocardial infarction (MI) in those with the lowest levels of T and DHT, but this association disappeared after adjusting for confounders.

However, since previous studies have linked low T with higher CVD mortality, the researchers suggest their