HIV transmission and benefits of lubrication

US researchers tested 14 popular water-based, silicone-based and lipid-based lubricants.

They found that iso-osmolar water-based and silicon-based lubricants were the least harmful to the epithelial tissue, while Gynol II, KY Jelly and Replens were the most toxic and also had a detrimental effect on lactobacillus viability in women, known to coincide with increased susceptibility to HIV infection.

Although some water-based products damaged tissue, when the lubricated tissue was exposed to HIV in the laboratory vulnerability was neither increased