HPV DNA test better than repeat Pap

The analysis found that triaging women with atypical squamous cells of undetermined significance (ASCUS) with high-risk HPV DNA testing was 27% more sensitive than repeating a Pap smear for detecting cervical intraepithelial neoplasia (CIN) grade 2+.

The study, which included more than 13,000 women with ASCUS across 39 studies, showed the specificity of a repeat smear was nearly identical to the specificity of HPV testing for excluding CIN2+.

However, while HPV testing was 23% more sensitive than repeat cytology for detecting CIN2+ in women with low