Ibuprofen reduces mountain sickness
The 86 hikers were randomised to receive either three doses of 600mg of ibuprofen or a placebo, administered over two days as they transitioned to an ultimate height of 12,570 feet above sea level.
Under half (43%) of those taking ibuprofen reported AMS compared to 69% in the placebo group. Symptom severity was also reduced though the result was non-significant.
“Ibuprofen could be a way to prevent AMS in a significant number of the tens of millions of people who travel to high altitudes each year,” the authors said.
Ann Emerg Med 2012, online 20 Mar