Is intensive glucose control so beneficial?

Compared with conventional control, intensive glucose control was associated with a reduced risk of microalbuminuria and macroalbuminuria. However, it was not associated with a reduced risk of doubling of the serum creatinine level, end-stage renal disease or death from renal disease during the trials’ follow-up years.

The authors concluded that given the low incidence of clinical renal outcomes combined with the “apparent lack of convincing benefit” for preventing chronic kidney disease and end