The key to turning off Alzheimer’s disease?
The mutation also seems to offer protection from the cognitive decline that occurs with age. While the mutation is very rare, it opens up possibilities to develop drugs that act on the same systems in the brain.
The gene mutation alters a gene that affects the production of plaques of amyloid beta which form in the brains of people with Alzheimer’s, reducing this production by 40%.
This discovery is particularly interesting because of the way the mutation works, by interfering with an enzyme BACE 1 to reduce the amount