Lifestyle changes reduce CVD risk in diabetes

Researchers undertook a 10-year follow-up of participants in the Diabetes Prevention Program (DPP), the largest diabetes prevention clinical trial in the US measuring lipids, blood pressure (BP) and annual medication of 2766 people with impaired glucose tolerance, half of whom went on to develop diabetes.

During the decade, participants spent three years on randomised treatment of metformin, intensive lifestyle intervention or placebo, a transitional year including lifestyle components and five years on the DPP Outcomes Study (DPPOS), which replicated the DPP but boosted the