Linking obesity and diabetes

Causality is a difficult concept in chronic disease. Rarely is it as simple as Koch’s Postulates for acute disease.

Attempts to assign a linear relationship to chronic diseases — that is, presence of risk equals development of disease — often fall short, like suggesting diet as a singular cause of heart disease.

Type 2 diabetes (T2D) is a case in point. The association between T2D and obesity — with 70—80% of T2D cases being overweight or