Lyme ‘encephalopathy’: it’s probably not caused by the bacteria

Patients concerned that headaches, fatigue and poor cognition mean that Lyme pathogens have infiltrated their brain might be experiencing the effects of their own immune system, a US study suggests.

Researchers examined serum and cerebrospinal fluid (CSF) samples from 74 patients undergoing lumbar puncture to test for Lyme neuroborreliosis.

They found a distinction between patients with definite neuroborreliosis and those who had Lyme encephalopathy, defined as a diagnosis of Lyme disease with neurobehavioural