Lymphocyte counts related to mortality risk in CHF

A LOW total lymphocyte count is inversely related to the mortality risk faced by patients with chronic heart failure, research suggests.

A longitudinal study by Israeli researchers found only 58% of 305 patients with chronic heart failure with an absolute lymphocyte count below 1600 survived after eight years, compared with 72% of patients with absolute lymphocyte counts above 1600. 

The class of heart failure had the strongest predictive value in the study, but lymphocyte count had better predictive value than mean left ventricular ejection fraction (LVEF).

Patients with lymphocyte counts 1600 or greater, and LVEF 40% above, had the best prognosis in the study.

Am J Cardiol 2011, online