Managing medication-overuse headache

A: Medication-overuse headache can be caused by prolonged use of any headache medication (e.g. triptans, paracetamol, NSAIDs, combination analgesics).1.2 Medication withdrawal is the only effective treatment.2-4

Consider specialist referral and inpatient withdrawal for people who overuse combinations of medications, or medications containing barbiturates, tranquilisers or opioids, as well as those with anxiety or depressive disorders.3.4