Metformin ‘useless’ in low-risk prediabetes

The US study of 3000 people with impaired glucose metabolism found not all patients benefited from metformin compared to lifestyle intervention.

“They have shown that the highest-risk group is almost entirely responsible [for metformin’s beneficial results] whereas the other three quarters didn’t respond at all, pretty much. It was a fairly useless treatment in the lowest three quartiles,” Associate Professor Neale Cohen, general manager of diabetes services at Baker IDI, said.

The researchers took data from

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