Methamphetamine link to schizophrenia risk

Researchers used hospital records to identify patients admitted for dependence or abuse of various drugs between 1990 and 2000. The study included 42,412 participants admitted for methamphetamine dependence and those with other drug use disorders, in addition to a “control group” of non-drug-using patients with appendicitis.

Researchers examined readmission records for schizophrenia diagnoses for up to 10 years later on all study participants.

Patients in the methamphetamine cohort had a significantly higher risk of schizophrenia diagnosis than non-drug users. 

Schizophrenia risk was higher in all the drug cohorts compared with the control group.

Am J Psychiatry; online 8 Nov