Methotrexate intolerance common

Research from Pakistan suggests up to a third of women taking methotrexate for rheumatoid arthritis may experience intolerance to the treatment.

The study of 150 women with RA used the methotrexate intolerance severity score (MISS) questionnaire to assess the prevalence of intolerance and other factors such as whether dosage or combination with other drugs had an effect.

Fifty of the patients scored 6 or