Methotrexate side effects under-recognised

Doctors may be underrating the significant side-effects of methotrexate treatment in rheumatoid arthritis, a new study finds.

Patients report side effects at a rate that is “appreciably higher” than prescribing information or anecdotal evidence would suggest, a survey of methotrexate and biologic users shows.

Among those taking methotrexate, 30% report at least some hair loss, between a third and a half have malaise and