MIMS May prescribing update

  • Lucassin (terlipressin) is a synthetic vasopressin analogue that acts as a systemic vasoconstrictor, via vasopressin 1a (V1a) receptors, both as a pro-drug for lysine-vasopressin and having pharmacologic activity on its own, albeit of lower potency than lysine-vasopressin. It increases mean arterial pressure and decreases heart rate while increasing systemic vascular resistance.
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