MIMS October prescribing update

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  • Lodotra (prednisone)is a nonfluorinated glucocorticoid for systemic therapy, which has a dose-dependent effect on the metabolism in almost all tissues. The mechanism of action of corticosteroids is thought to be by control of protein synthesis. In the Lodotra modified release tablets dosages typically prescribed, prednisone has an immediate anti-inflammatory (antiexudative and antiproliferative) effect and a delayed immunosuppressive effect. It inhibits chemotaxis and the activity of immune cells, as well

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