Mountaineers shed light on diabetes mechanism: study

UK researchers have compared the effect of hypoxia in 12 healthy individuals who trekked to the Everest Base Camp (5300m), with the effect in 12 who climbed as high as 8848m.

The team, from the University of Southampton, found markers of insulin resistance were increased in those exposed to hypoxia during the six- to eight-week study.

As fat tissue in people with obesity behaves in a similar manner to tissue in chronic mild hypoxia, observation of the climbers offered clues to combatting progression to diabetes in at-risk individuals, such as

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