New generation of stress
According to a US study, sons of male mice exposed to prenatal stress are more sensitive to stress as adults.
It has previously been shown that male mice are sensitive to stress when their mothers have experienced stress during pregnancy. In this study, researchers bred stress-sensitive males with normal females and found male offspring displayed a pronounced reaction to stress just like their fathers, though there had been no additional exposure to stress in the womb.
Stress-sensitive grandsons also had smaller testes, as did their fathers, suggesting they were exposed to less testosterone around birth.
J Neurosci 2011; 17;31:11748-55