New strategy to boost malaria survival?

Australian researchers have shown that a new class of anti-inflammatory agent, innate defence regulator (IDR) peptides, could help to increase survival when used in combination with antimalarial drugs.

In studies in mouse models the team showed the new drug prevented inflammation, potentially improving survival.

“This is an example of a ‘host-directed’ therapy – a treatment intended to act on the host not the parasite,” the authors said.