New test could simplify coeliac diagnosis

A diagnosis for coeliac disease may soon be possible without the need for prolonged gluten exposure, researchers say.

Dr Jason Tye-Din, a gastroenterologist and head of coeliac research at the Walter and Eliza Hall Institute in Melbourne and colleagues developed a ‘cytokine release’ test measuring the T cell response to gluten after three days of consumption.

He and his team were able to detect a T cell response in the majority of the 48 participants known to have coeliac disease.

The test was also negative in all of the patients who did not have the disease, even though they