New transcranial stimulation may be option for major depression

ECT is considered the most effective treatment for the 30% of patients with depression who do not respond to medication, despite downsides including cognitive impairment and confusion.

Magnetic seizure therapy (MST), which uses high frequency repetitive transcranial magnetic stimulation, has been shown to have similar clinical effects to ECT, without the side effects, in a trial at the Monash Alfred Psychiatry Research Centre.

The 10-patient study found MST reduced depression symptoms, with 40% showing overall improvement and 30% “some” improvement.

The research centre’s deputy