NSAIDs differ in risk for hypertension: study

Compared with celecoxib, use of ibuprofen leads to increased blood pressure among patients with arthritis who are also at risk for cardiovascular disease (CVD), a study shows.

A randomised trial of 444 patients seeking relief from the pain of osteoarthritis or rheumatoid arthritis showed differences in mean systolic blood pressure (SBP) after four months on one of three NSAIDS.

All patients enrolled in the PRECISION-ABPM trial, funded by celecoxib sponsor Pfizer, either had pre-existing CVD or were at high risk of it. The mean age was 62 years and the majority (92%) had