Obese girls may have raised risk of multiple sclerosis

The authors identified 75 children diagnosed with paediatric MS or its potential precursor, clinically isolated syndrome (CIS), from a California cohort and compared them to >900,000 controls. 

Most of those with MS or CIS (54.7%) were female. More than half had high BMI compared to 36.6% of the children who did not have MS/CIS. 

The odds of developing MS/CIS was more than 1.5 times higher for overweight girls, 1.8 times higher in moderately obese girls and almost four times higher in extremely obese girls. The association was not found in boys. 

Neurology 2013; online 30 Jan