Oestrogen therapy and ovarian cancer risk
A RECENT meta-analysis reported an increased risk of ovarian cancer in women using menopausal hormone therapy.
So how will this finding impact clinical practice?
In the study (Lancet, online 15 Feb, 2015), investigators examined individual datasets from 52 prospective and retrospective epidemiological studies from Europe and North America.
The principal analysis involved the prospective studies, while sensitivity analyses included the retrospective studies.
Results showed that compared to never users, current or recent users