Orthostatic hypotension linked with dementia and stroke

Recurrent cerebral hypoperfusion may be the cause

Having orthostatic hypotension (OH) in middle-age may bring increased risk of dementia or ischaemic stroke later in life, a US study shows.

A community-based study of over 11,000 people with a mean age of 54 years showed that the 552 participants with OH had a 54% higher risk of developing dementia and twice the risk of having an ischemic stroke, compared to those without the condition.

The sub-study analysed data from the large Atherosclerosis Risk in Communities study, which included participants with no previous history of coronary heart disease or stroke and an