Ovarian cancer algorithm assists ultrasound triage
The study used the Risk of Ovarian Cancer Algorithm (ROCA) developed using data from 27,000 UK and Swedish women. Women with high-risk scores had ultrasound which determined whether surgery was indicated. The protocol gave a positive predictive value of 40%, exceeding the minimum clinical benchmark of 10%, and a specificity of 99.9%,the researchers said.
“The PPV in our study... demonstrates that no more than two to three operations were needed to detect one case of invasive ovarian cancer.”
Cancer 2013; online 26 August