Paracetamol findings contradict GP guidelines
A WIDE-RANGING meta-analysis has concluded there is “no role” for paracetamol in the treatment of osteoarthritis.
The Lancet review of 74 trials of paracetamol and seven different NSAIDs with nearly 60,000 patients found diclofenac 15mg/day to be the most effective for short-term pain relief.
Other treatments that scored well were etoricoxib 60mg/day and rofecoxib 25mg/day, both of which had a 100% probability of exceeding the minimum standard for clinical efficacy.
However, paracetamol, which is widely used in OA, performed