PBS listing for new-generation epilepsy drug

The first in a new class of drugs to treat partial onset seizure could offer a solution to drug-resistant epilepsy, says a leading Australian neurologist.

Perampanel, which was approved for reimbursement on the PBS from November, is the only available AED to selectively target AMPA receptors implicated in the spread of seizures. It is indicated as an adjunctive treatment for patients who have failed previous antiepileptic drugs.