Periodontitis associated with smoking in seropositive RA

The link between smoking and periodontitis in patients with rheumatoid arthritis only applies if they have seropositive disease, a Swedish study shows.

Compared with never smokers, current smokers with RA and antibodies to citrullinated protein antigens (ACPA) had almost double the risk of periodontitis, the study of 2327 patients showed.

The risk of the gum disease was also almost double in RA patients positive for rheumatoid factor (RF) and current smokers.    

The greatest risk was in men who were current smokers and seropositive for both ACPA and RF,