Phage therapy: the answer to antibiotic resistance, but not yet

IN THE previous article, the history and development of knowledge on bacteriophages was discussed. This article examines some principles of using bacteriophages for treatment (‘phage therapy’).

Phage therapy refers to the targeted use of bacteriophages to destroy pathogenic bacteria. As described in the previous article, phage therapy fell by the wayside following the advent of antibiotics, especially considering the dramatic success of penicillin. In 1980, in the United Kingdom, a veterinary surgeon, William Smith, carried out a series of impeccably well