Pumps trump injections, insulin study shows
The study of 345 children with type 1 diabetes, followed for up to 10 years at Princess Margaret Hospital for Children, Perth, found the mean HbA1c reduction in the pump cohort was 0.6% (6.6mmol/mol) when compared to matched controls on injections.
This was described as clinically significant, with microvascular complications reported to decrease by 21–49% with every 1% reduction in HbA1c.
Improved HbA1c remained significant until seven years of follow-up, at which point the authors said the numbers were too small to analyse the results with statistical confidence.
Pump therapy was found to reduce episodes of severe hypoglycaemia from 14.7 to 7.2 events per 100 patients per year, compared to an increase in the non-pump cohort.
The rate of admission for diabetic ketoacidosis was also lower in the pump cohort than in the non-pump cohort. The authors said the effectiveness of insulin pump therapy continues to be debated, despite