Raised dementia risk with high BGL but no diabetes

In a study of more than 2000 people with no dementia and a mean age of 76 years, US researchers measured glucose levels at baseline, finding 232 had diabetes.

Dementia developed in 524 participants during nearly seven years of follow-up. Among those without diabetes, the risk of dementia increased with increasing glucose levels – an 18% increased risk for an average 6.4mmol/L compared to 5.5mmol/L.

Potential mechanisms may include increased microvascular disease of the central nervous system, they said.