Ramipril may relieve claudication
The Baker IDI Heart & Diabetes Institute found the generic ACE inhibitor improved maximum walking times on a treadmill test by 123% (255 seconds) compared to placebo in 212 PAD patients treated with 10mg a day for 24 weeks. Participants also experienced a 77% increase (75 seconds) in pain-free walking.
Baker IDI researcher Professor Bronwyn Kingwell said there might be a class effect. She said they wanted to get ramipril recognised as a treatment for claudication.
JAMA 2013; online 6 Feb