Rectal chlamydia treatment failure rates high
According to epidemiologist Associate Professor Jane Hocking from the University of Melbourne’s School of Population and Global Health, there has been growing concern about treatment for rectal chlamydia with treatment failures of up to 22% being reported.
Based on prevalence estimates from sexual health clinics in Australia about 5—7% of men who have sex with men (MSM) will experience rectal chlamydia infection, she said.
“That’s reasonably high among men attending those clinics but there has been concern about the potential for rectal chlamydia treatment failure when it is treated with 1g of azithromycin as has been previously recommended.”
Professor Hocking said several reasons have been suggested to explain why azithromycin does not work as well for rectal chlamydia as it does for cervical or urethral infection but with no clinical trials looking specifically at azithromycin for rectal infection it is hard to know