Researcher monitors own diabetes development

Professor Michael Snyder of Stanford University discovered he had an elevated type 2 diabetes risk by sequencing his own genome.

Over 14 months of monitoring his ‘omics profile’, a combined analysis of genomic sequence, and gene, protein, metabolic and autoantibody expression, he was diagnosed with type 2 diabetes after 12 months, following a respiratory syncytial viral infection.

After implementing dramatic lifestyle changes, his HbA1c fell from 6.7% to 4.7% at 20 months.

“Our study indicates disease risk can be assessed from a genome sequence and illustrates how traits associated with disease can be monitored to identify varying physiological stages,” the authors said.

Cell 2012: 148;1293-1307

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