Researchers discover insulin-resistance trigger

Researchers believe they have identified a mechanism that triggers the events leading to insulin resistance in obese patients.

They describe the process in a study that shows men with metabolic syndrome have higher levels of molecule NBR1, which is correlated with markers of inflammation.

They also describe an experiment that shows mice in which NBR1 is genetically inactivated have less inflammation and less glucose intolerance than normal mice.

Another experiment shows NBR1