Review of codeine safety fuels rescheduling debate

THE first systematic review of the safety and efficacy of combination OTC codeine products finds no robust evidence to back their potential for dependency but documents their potential harms, adding fuel to the hotly contested codeine scheduling debate.

The independent review, conducted by medicine safety experts on behalf of the TGA, also found evidence that the products worked, mainly in the short term, with stronger evidence for analgesia than for cough suppression.

The TGA posted the review on its website last Thursday and is expected to release an update in June on