RF ablation effective in Barrett’s with low-grade dysplasia

Radiofrequency ablation (RFA) is far more effective than endoscopic surveillance at cutting the risk of progression to cancer in Barrett’s oesophagus with low-grade dysplasia, Dutch researchers find.

In pathologist-confirmed low-grade dysplasia, RFA cut the absolute risk of progression to high-grade dysplasia or adenocarcinoma within three years by a quarter compared with endoscopic surveillance (1.5% vs 26.5%), data from the randomised trial of 136 patients showed.

Absolute risk of progression to adenocarcinoma only was cut by 7.4%