Right-sided tumour more lethal
Drawing on data from nearly 3000 patients in the SA metastatic colorectal cancer registry, researchers showed those with a right-sided primary tumour were 25% more likely to die than those with a left-sided one.
Right primaries were more common among women and more likely to be associated with the KRAS exon 2 mutation.
Overall median survival among the cohort was 9.7 months for right primary and 20.3 months for left, including those who had no active therapy. Among those having chemotherapy, with or without metastasis resection, median survival was 18.2 months for right primary versus 29.4 months for left