Specialist Updates

Rising placebo effect theory debunked

The average placebo response rate for antidepressants in the acute treatment of major depression has remained steady at 35-40% over the past two decades.

The findings, from an extensive review of randomised antidepressant trials, debunk the myth of rising placebo responses.

They also shed new light on the heated debate over the diminishing efficacy of antidepressant drugs.