Scientists discover new hormone’s role in type 2
Researchers have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver.
Their mouse study shows neuregulin 4 hormone (Nrg4) is secreted by so-called brown fat cells and communicates with the liver to regulate the conversion of sugar into fat.
Mice without NRG4 become obese and develop hallmarks of type 2 diabetes and fatty liver disease, according to the article in the journal Nature Medicine.
However, when the researchers genetically elevated Nrg4 levels in the mice, the animals were protected from metabolic disorders