Scientists find steps that lead to pancreatic cancer

US researchers have identified a cellular process that leads to pancreatic cancer, according to a research article that describes the molecular steps necessary for acinar cells to become precancerous lesions.

"If we understand how these lesions come about, we may be able to stop the cancer train altogether," says lead investigator Dr Peter Storz, a Mayo Clinic cancer biologist whose study is published in the journal Cancer Discovery.

His team studied pancreatic cells with Kras genetic mutations, which are present in 95% of pancreatic cancer cases,