Screening for abnormal glucose tolerance

The research involved a cross-sectional study of 254 children, aged 10–17 years, with a BMI of at least the 85th percentile. Tests included a fasting and a two-hour glucose tolerance test, HbA1c and fructosamine testing, as well as random glucose testing and urine dipstick analysis.

Results showed that 39% of the participants had prediabetes, and 1.2% had diabetes, with a formal two-hour oral glucose tolerance test. Discrimination was poor with HbA1c and fructosamine testing. Both random glucose and one-hour glucose challenge testing had better levels of test discrimination. 

Diabetes Care, online 27 Sept