Screening in pregnancy no benefit in Q fever outbreak

The Netherlands experienced one of the largest outbreaks of Q fever between 2007 and 2010, leading to investigation in a randomised controlled trial of whether screening for Coxiella burnetii would reduce obstetric complications.

However, the study, involving nearly 7000 women in maternity centres across the country, found no clear difference in outcomes of seropositive women, whether they were assigned to the intervention group whose blood was analysed immediately and treatment offered, or to a control group